Literature Survey

Electrospray-Ionization Mass Spectrometry of Lipids 2010 onwards

Electrospray-ionization (ESI) mass spectrometry is now in all probability the most popular technique for non-volatile lipids, such as triacylglycerols, phospholipids and glycolipids. Because of the popularity of the technique we have had to split the survey into parts - the first one up to 2004 and then from 2005 to 2009. It can give a great deal of invaluable information, including the nature of any polar head group, molecular species composition and regiospecific distributions of fatty acids on the glycerol backbone.

The following references were collected as part of our regular literature reviews for our own research purposes. We cannot claim to have covered the subject exhaustively, but we have done our best. References are listed alphabetically by the first author of a paper, but not necessarily chronologically by that author. New references may be added at irregular intervals - check the bottom of the page for when it was last updated.

  • Abbott, S.K., Jenner, A.M., Mitchell, T.W., Brown, S.H.J., Halliday, G.M. and Garner, B. An improved high-throughput lipid extraction method for the analysis of human brain lipids. Lipids, 48, 307-318 (2013).
  • Acheampong, A., Leveque,N., Tchapla,A. and Heron,S. Simple complementary liquid chromatography and mass spectrometry approaches for the characterization of triacylglycerols in Pinus koraiensis seed oil. J. Chromatogr. A, 1218, 5087-5100 (2011).
  • Akmurzina, V. A., Petryaikina, E.E., Saveliev, S.V. and Selishcheva, A.A. Using high-performance liquid chromatography/mass spectrometry for the quantification of plasma phospholipids in children with type 1 diabetes. J. Anal. Chem., 68, 1170-1177 (2013).
  • Aljohani, A.J., Munguba, G.C., Guerra, Y., Lee, R.K. and Bhattacharya, S.K. Sphingolipids and ceramides in human aqueous humor. Mol. Vision, 19, 1966-1984 (2013).
  • Andreyev, A.Y., Fahy,E., Guan,Z.Q., Kelly,S., Li,X.A., McDonald,J.G., Milne,S., Myers,D., Park,H., Ryan,A., Thompson,B.M., Wang,E., Zhao,Y.H., Brown,H.A., Merrill,A.H., Raetz,C.R.H., Russell,D.W., Subramaniam,S. and Dennis,E.A. Subcellular organelle lipidomics in TLR-4-activated macrophages. J. Lipid Res., 51, 2785-2797 (2010).
  • Arroyo-Abad, U., Lischka, S., Piechotta, C., Mattusch, J. and Reemtsma, T. Determination and identification of hydrophilic and hydrophobic arsenic species in methanol extract of fresh cod liver by RP-HPLC with simultaneous ICP-MS and ESI-Q-TOF-MS detection. Food Chem., 141, 3093-3102 (2013).
  • Arutchelvi, J. and Doble,M. Characterization of glycolipid biosurfactant from Pseudomonas aeruginosa CPCL isolated from petroleum-contaminated soil. Letts Appl. Microbiol., 51, 75-82 (2010).
  • Asakawa, D., Yoshimura,K., Takeda,S. and Hiraoka,K. Direct analysis of lipids in mouse brain using electrospray droplet impact/SIMS. J. Mass Spectrom., 45, 437-443 (2010).
  • Axelsen, P.H. and Murphy,R.C. Quantitative analysis of phospholipids containing arachidonate and docosahexenoate chains in microdissected regions of mouse brain. J. Lipid Res., 51, 660-671 (2010).
  • Bai, H.Y., Lin,S.L., Chung,Y.T., Liu,T.Y., Chan,S.A. and Fuh,M.R. Quantitative determination of 8-isoprostaglandin F-2 alpha in human urine using microfluidic chip-based nano-liquid chromatography with on-chip sample enrichment and tandem mass spectrometry. J. Chromatogr. A, 1218, 2085-2090 (2011).
  • Balgoma, D., Astudillo,A.M., Perez-Chacon,G., Montero,O., Balboa,M.A. and Balsinde,J. Markers of monocyte activation revealed by lipidomic profiling of arachidonic acid-containing phospholipids. J. Immunol., 184, 3857-3865 (2010).
  • Balgoma, D., Montero,O., Balboa,M.A. and Balsinde,J. Lipidomic approaches to the study of phospholipase A(2)-regulated phospholipid fatty acid incorporation and remodelling. Biochimie, 92, 645-650 (2010).
  • Balvers, M.G.J., Wortelboer, H.M., Witkamp, R.F. and Verhoeckx, K.C.M. Liquid chromatography-tandem mass spectrometry analysis of free and esterified fatty acid N-acyl ethanolamines in plasma and blood cells. Anal. Biochem., 434, 275-283 (2013).
  • Banoub, J.H., El Aneed,A., Cohen,A.M. and Joly,N. Structural investigation of bacterial lipopolysaccharides by mass spectrometry and tandem mass spectrometry. Mass Spectrom. Rev., 29, 606-650 (2010).
  • Baronio, M., Lattanzio,V.M.T., Vaisman,N., Oren,A. and Corcelli,A. The acylhalocapnines of halophilic bacteria: structural details of unusual sulfonate sphingoids. J. Lipid Res., 51, 1878-1885 (2010).
  • Basile, F., Sibray,T., Belisle, J.T. and Bowen,R.A. Analysis of lipids from crude lung tissue extracts by desorption electrospray ionization mass spectrometry and pattern recognition. Anal. Biochem., 408, 289-296 (2011).
  • Bauersachs, T., Speelman,E.N., Hopmans,E.C., Reichart,G.J., Schouten,S. and Damste,J.S.S. Fossilized glycolipids reveal past oceanic N-2 fixation by heterocystous cyanobacteria. Proc.Nat. Acad. Sci. USA, 107, 19190-19194 (2010).
  • Beck, S., Muller,F.D., Strauch,E., Brecker,L. and Linscheid,M.W. Chemical structure of Bacteriovorax stolpii Lipid A. Lipids, 45, 189-198 (2010).
  • Beneito-Cambra, M., Bernabe-Zafon,V., Simo-Alfonso,E.F. and Ramis-Ramos,G. Chromium(VI) oxide oxidation of non-ethoxylated and ethoxylated alcohols for determination by electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom., 24, 2093-2100 (2010).
  • Berdeaux, O., Juaneda,P., Martine,L., Cabaret,S., Bretillon,L. and Acar,N. Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry. J. Chromatogr. A, 1217, 7738-7748 (2010).
  • Berdyshev, E.V., Goya,J., Gorshkova,I., Prestwich,G.D., Byun,H.S., Bittman,R. and Natarajan,V. Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. Anal. Biochem., 408, 12-18 (2011).
  • Bhamidi, S., Scherman,M.S., Jones,V., Crick,D.C., Belisle,J.T., Brennan,P.J. and McNeil,M.R. Detailed structural and quantitative analysis reveals the spatial organization of the cell walls of in vivo grown Mycobacterium leprae and in vitro grown Mycobacterium tuberculosis. J. Biol. Chem., 286, 23168-23177 (2011).
  • Bicalho, B., Holovati, J.L. and Acker, J.P. Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles. Biochim. Biophys. Acta, 1828, 317-326 (2013).
  • Bielawski, J., Pierce, J.S., Snider, J., Rembiesa, B., Szulc, Z.M. and Bielawska, A. Sphingolipid analysis by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Adv Exp Med Biol., 688, 46-59 (2010).
  • Bird, S.S., Marur,V.R., Sniatynski,M.J., Greenberg,H.K. and Kristal,B.S. Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins. Anal. Chem., 83, 940-949 (2011).
  • Bird, S.S., Marur,V.R., Sniatynski,M.J., Greenberg,H.K. and Kristal,B.S. Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: focus on triglyceride detection and characterization. Anal. Chem., 83, 6648-6657 (2011).
  • Bird, S.S., Marur, V.R., Stavrovskaya, I.G. and Kristal, B.S. Separation of cis-trans phospholipid isomers using reversed phase LC with high resolution MS detection. Anal. Chem., 84, 5509-5517 (2012).
  • Blaas, N. and Humpf, H.U. Structural profiling and quantitation of glycosyl inositol phosphoceramides in plants with Fourier transform mass spectrometry. J. Agric. Food Chem., 61, 4257-4269 (2013).
  • Blaas, N., Schuurmann,C., Bartke,N., Stahl,B. and Humpf,H.U. Structural profiling and quantification of sphingomyelin in human breast milk by HPLC-MS/MS. J. Agric. Food Chem., 59, 6018-6024 (2011).
  • Blachnio-Zabielska, A.U., Koutsari,C. and Jensen, M.D. Measuring long-chain acyl-coenzyme A concentrations and enrichment using liquid chromatography/tandem mass spectrometry with selected reaction monitoring. Rapid Commun. Mass Spectrom., 25, 2223-2230 (2011).
  • Blachnio-Zabielska, A.U., Persson, X.M.T., Koutsari, C., Zabielski, P. and Jensen, M.D. A liquid chromatography/tandem mass spectrometry method for measuring the in vivo incorporation of plasma free fatty acids into intramyocellular ceramides in humans. Rapid Commun. Mass Spectrom., 26, 1134-1140 (2012).
  • Blachnio-Zabielska, A.U., Zabielski, P. and Jensen, M.D. Intramyocellular diacylglycerol concentrations and [U-C-13]palmitate isotopic enrichment measured by LC/MS/MS. J. Lipid Res., 54, 1705-1711 (2013).
  • Blair, I.A. Analysis of endogenous glutathione-adducts and their metabolites. Biomed. Chromatogr., 24, 29-38 (2010).
  • Blanksby, S.J. and Mitchell,T.W. Advances in mass spectrometry for lipidomics. Ann. Rev. Anal. Chem., 3, 433-465 (2010).
  • Boath, A., Graf,C., Lidome,E., Ullrich,T., Nussbaumer,P. and Bornancin,F. Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase. Comparative analysis to glucosylceramide and sphingomyelin. J. Biol. Chem., 283, 8517-8526 (2008).
  • Bollinger, J.G., Ii,,H., Sadilek,M. and Gelb,M.H. Improved method for the quantification of lysophospholipids including enol ether species by liquid chromatography-tandem mass spectrometry. J. Lipid Res., 51, 440-447 (2010).
  • Bollinger, J.G., Thompson,W., Lai,Y., Oslund,R.C., Hallstrand,T.S., Sadilek,M., Turecek,F. and Gelb,M.H. Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization. Anal. Chem., 82, 6790-6796 (2010).
  • Botté, C.Y., Yamaryo-Botté,Y., Janouskovec,J., Rupasinghe,T., Keeling,P.J., Crellin,P., Coppel,R.L., Maréchal,E., McConville,M.J. and McFadden,G.I. Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites. J. Biol. Chem., 286, 29893-29903 (2011).
  • Bowden, J.A., Albert,C.J., Barnaby,O.S. and Ford,D.A. Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry. Anal. Biochem., 417, 202-210 (2011).
  • Bowden, J.A., Shao,F., Albert,C.J., Lally,J.W., Brown,R.J., Procknow,J.D., Stephenson,A.H. and Ford,D.A. Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters. Lipids, 46, 1169-1179 (2011)
  • Bowen, C.L., Kehler,J. and Evans,C.A. Development and validation of a sensitive and selective UHPLC-MS/MS method for simultaneous determination of both free and total eicosapentaeonic acid and docosahexenoic acid in human plasma. J. Chromatogr. B, 878, 3125-3133 (2010).
  • Brady, J.J., Judge,E.J. and Levis,R.J. Analysis of amphiphilic lipids and hydrophobic proteins using nonresonant femtosecond laser vaporization with electrospray post-ionization. J. Am. Soc. Mass Spectrom., 22, 762-772 (2011).
  • Brouwers, J.F. Liquid chromatographic-mass spectrometric analysis of phospholipids. Chromatography, ionization and quantification. Biochim. Biophys. Acta, 1811, 763-775 (2011)
  • Brunnstrom, A., Hamberg,M., Griffiths,W.J., Mannervik,B. and Claesson,H.E. Biosynthesis of 14,15-hepoxilins in human L1236 Hodgkin lymphoma cells and eosinophils. Lipids, 46, 69-79 (2011).
  • Buczynski, M.W., Svensson,C.I., Dumlao,D.S., Fitzsimmons,B.L., Shim,J.H., Scherbart,T.J., Jacobsen,F.E., Hua,X.Y., Yaksh,T.L. and Dennis,E.A. Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord. J. Neurochem., 114, 981-993 (2010).
  • Bui, H.H., Leohr, J.K. and Kuo, M.S. Analysis of sphingolipids in extracted human plasma using liquid chromatography electrospray ionization tandem mass spectrometry. Anal. Biochem., 423, 187-194 (2012).
  • Bure, C., Ayciriex, S., Testet, E. and Schmitter, J.M. A single run LC-MS/MS method for phospholipidomics. Anal. Bioanal. Chem.,405, 203-213 (2013).
  • Burgos, A., Szymanski,J., Seiwert,B., Degenkolbe,T., Hannah,M.A., Giavalisco,P. and Willmitzer,L. Analysis of short-term changes in the Arabidopsis thaliana glycerolipidome in response to temperature and light. Plant J., 66, 656-668 (2011).
  • Bütikofer, P., Greganova,E., Liu,Y.-C., Edwards,I.J., Lehane,M.J. and Acosta-Serrano,A. Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited. Biochem. J., 428, 409–418 (2010).
  • Butovich, I.A. Fatty acid composition of cholesteryl esters of human meibomian gland secretions. Steroids, 75, 726-733 (2010).
  • Byeon, S.K., Lee, J.Y. and Moon, M.H. Optimized extraction of phospholipids and lysophospholipids for nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry. Analyst, 137, 451-458 (2012).
  • Byrdwell, W.C. Dual parallel mass spectrometry for lipid and vitamin D analysis. J. Chromatogr. A, 1217, 3992-4003 (2010).
  • Byrdwell, W.C. Quadruple parallel mass spectrometry for analysis of vitamin D and triacylglycerols in a dietary supplement. J. Chromatogr. A, 1320, 48-65 (2013).
  • Cacas, J.-L., Buré , C., Furt, F., Maalouf, J.-P.., Badoc, A., Cluzet, S., Schmitter, J.-M., Antajan, E. and Mongrand, S. Biochemical survey of the polar head of plant glycosylinositolphosphoceramides unravels broad diversity. Phytochemistry, 96, 191-200 (2013).
  • Camera, E., Ludovici,M., Galante,M., Sinagra,J.L. and Picardo,M. Comprehensive analysis of the major lipid classes in sebum by rapid resolution high-performance liquid chromatography and electrospray mass spectrometry. J. Lipid Res., 51, 3377-3388 (2010).
  • Cabarcos, P., Cocho, J.A., Moreda, A., Miguez, M., Tabernero, M.J., Fernandez, P. and Bermejo, A.M. Application of dispersive liquid-liquid microextraction for the determination of phosphatidylethanol in blood by liquid chromatography tandem mass spectrometry. Talanta, 111, 189-195 (2013).
  • Carillo, S., Pieretti, G., Lindner, B., Romano, I., Nicolaus, B., Lanzetta, R., Parrilli, M. and Corsaro, M.M. The Lipid A from the haloalkaliphilic bacterium Salinivibrio sharmensis strain BAG(T). Marine Drugs, 11, 184-193 (2013).
  • Castro-Perez, J.M., Kamphorst,J., DeGroot,J., Lafeber,F., Goshawk,J., Yu,K., Shockcor,J.P., Vreeken,R.J. and Hankemeier,T. Comprehensive LC-MSE lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients. J. Proteome Res., 9, 2377-2389 (2010).
  • Castro-Perez, J., Roddy,T.P., Nibbering,N.M.M., Shah,V., McLaren,D.G., Previs,S., Attygalle,A.B., Herath,K., Chen,Z., Wang,S.P., Mitnaul,L., Hubbard,B.K., Vreeken,R.J., Johns,D.G. and Hankemeier,T. Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry. J. Am. Soc. Mass Spectrom., 22, 1552-1567 (2011).
  • Cataldi, T.R.I., Bianco,G., Abate,S. and Losito,I. Identification of unsaturated N-acylhomoserine lactones in bacterial isolates of Rhodobacter sphaeroides by liquid chromatography coupled to electrospray ionization-hybrid linear ion trap-Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun. Mass Spectrom., 25, 1817-1826 (2011).
  • Castro-Perez, J., Roddy,T.P., Nibbering,N.M.M., Shah,V., McLaren,D.G., Previs,S., Attygalle,A.B., Herath,K., Chen,Z., Wang,S.P., Mitnaul,L., Hubbard,B.K., Vreeken,R.J., Johns,D.G. and Hankemeier,T. Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry. J. Am. Soc. Mass Spectrom., 22, 1552-1567 (2011).
  • Chan, R.B., Oliveira, T.G., Cortes, E.P., Honig, L.S., Duff, K.E., Small, S.A., Wenk, M.R., Shui, G.H. and Di Paolo, G. Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. J. Biol. Chem., 287, 2678-2688 (2012).
  • Chappell, G.P., Xiao,X.Y., Pica-Mendez,A., Varnell,T., Green,S., Tanaka,W.K. and Laterza,O. Quantitative measurement of cysteinyl leukotrienes and leukotriene B-4 in human sputum using ultra high pressure liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 879, 277-284 (2011).
  • Chechetkin, I.R., Blufard, A.S., Khairutdinov, B.I., Mukhitova, F.K., Gonna, S.S., Yarin, Andrey Y., Antsygina, L.L. and Grechkin, A.N. Isolation and structure elucidation of linolipins C and D, complex oxylipins from flax leaves. Phytochemistry, 96, 110-116 (2013).
  • Chen, J.Z., Green, K.B. and Nichols, K.K. Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometry. Invest. Ophthalmol. Vis. Sci., 54, 5730-5753 (2013).
  • Chen, J.Z., Green-Church,K.B. and Nichols,K.K. Shotgun lipidomic analysis of human meibomian gland secretions with electrospray ionization tandem mass spectrometry. Invest. Ophthalmol. Vis. Sci., 51, 6220-6231 (2010).
  • Chen, S., Belikova, N.A. and Subbaiah, P.V. Structural elucidation of molecular species of pacific oyster ether amino phospholipids by normal-phase liquid chromatography/negative-ion electrospray ionization and quadrupole/multiple-stage linear ion-trap mass spectrometry. Anal. Chim. Acta, 735, 76-89 (2012).
  • Chen, Y., Ogundare, M., Williams, C.M., Wang, Y., Wang, Y., Sewell, G.W., Smith, P.J., Rahman, F.Z., O'Shea, N., Segal, A.W. and Griffiths, W.J. Shotgun cholanomics of ileal fluid. Biochimie, 95, 461-463 (2013).
  • Chitraju, C., Trotzmuller, M., Hartler, J., Wolinski, H., Thallinger, G.G., Lass, A., Zechner, R., Zimmermann, R., Kofeler, H.C. and Spener, F. Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress. J. Lipid Res., 53, 2141-2152 (2012).
  • Christie, W.W. and Han, X. Lipid Analysis - Isolation, Separation, Identification and Lipidomic Analysis (4th edition), 446 pages (Oily Press, Bridgwater, U.K. and Woodhead Publishing Ltd, Cambridge, U.K.) (2010) - Woodhead Publishing Ltd.
  • Cifkova, E., Holcapek, M. and Lisa, M. Nontargeted lipidomic characterization of porcine organs using hydrophilic interaction liquid chromatography and off-line two-dimensional liquid chromatography-electrospray ionization mass spectrometry. Lipids, 48, 915-928 (2013).
  • Cifkova, E., Holcapek, M., Lisa, M., Ovcacikova, M., Lycka, A., Lynen, F. and Sandra, P. Nontargeted quantitation of lipid classes using hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry with single internal standard and response factor approach. Anal. Chem., 84, 10064-10070 (2012).
  • Claria, J., Nguyen, B.T., Madenci, A.L., Ozaki, C.K. and Serhan, C.N. Diversity of lipid mediators in human adipose tissue depots. Am. J. Physiol.-Cell Physiol., 304, C1141-C1149 (2013).
  • Cutignano, A., Chiuminatto,U., Petruzziello,F., Vella,F.M. and Fontana,A. UPLC-MS/MS method for analysis of sphingosine 1-phosphate in biological samples. Prostaglandins Other Lipid Mediators, 93, 25-29 (2010).
  • Costantino, V., Fattorusso,E., Mangoni,A., Teta,R., Panza,E. and Ianaro,A. Terpioside B, a difucosyl GSL from the marine sponge Terpios sp is a potent inhibitor of NO release. Bioorg. Med. Chem., 18, 5310-5315 (2010).
  • Cozzolino, R. and De Giulio,B. Application of ESI and MALDI-TOF MS for triacylglycerols analysis in edible oils. Eur. J. Lipid Sci. Technol., 113, 160-167 (2011).
  • Cutignano, A., Lamari,N., d'Ippolito,G., Manzo,E., Cimino,G. and Fontana,A. Lipoxygenase products in marine diatoms: a concise analytical method to explore the functional potential of oxylipins. J. Phycol., 47, 233-243 (2011).
  • Dahl, J.H. and van Breemen,R.B. Rapid quantitative analysis of 8-iso-prostaglandin-F-2 alpha using liquid chromatography-tandem mass spectrometry and comparison with an enzyme immunoassay method. Anal. Biochem., 404, 211-216 (2010).
  • Damste, J.S.S., Rijpstra, W.I.C., Hopmans, E.C., Jung, M.Y., Kim, J.G., Rhee, S.K., Stieglmeier, M. and Schleper, C. Intact polar and core glycerol dibiphytanyl glycerol tetraether lipids of group i.1a and i.1b Thaumarchaeota in soil. Appl. Environm. Microbiol., 78, 6866-6874 (2012).
  • Dashti,M., Kulik, W., Hoek, F., Veerman, E.C., Peppelenbosch, M.P. and Rezaee, F. A phospholipidomic analysis of all defined human plasma lipoproteins. Scientific Rep., 1, 139 (2011).
  • De Jonge, C., Hopmans, E.C., Stadnitskaia, A., Rijpstra, W.I.C., Hofland, R., Tegelaar, E. and Damste, J.S.S. Identification of novel penta- and hexamethylated branched glycerol dialkyl glycerol tetraethers in peat using HPLC-MS2, GC-MS and GC-SMB-MS. Org. Geochem., 54, 78-82 (2013).
  • Deng, L., Fukuda,R., Kakihara,T., Narita,K. and Ohta,A. Incorporation and remodeling of phosphatidylethanolamine containing short acyl residues in yeast. Biochim. Biophys. Acta, 1801, 635-645 (2010).
  • Dennis ,E.A. and 27 others. A mouse macrophage lipidome. J. Biol. Chem., 285, 39976-39985 (2010).
  • Dill, A.L., Eberlin,L.S., Zheng,C., Costa,A.B., Ifa,D.R., Cheng,L.A., Masterson,T.A., Koch,M.O., Vitek,O. and Cooks,R.G. Multivariate statistical differentiation of renal cell carcinomas based on lipidomic analysis by ambient ionization imaging mass spectrometry. Anal. Bioanal. Chem. 398, 2969-2978 (2010).
  • Divito, E.B., Davic, A.P., Johnson, M.E. and Cascio, M. Electrospray ionization and collision induced dissociation mass spectrometry of primary fatty acid amides. Anal. Chem., 84, 2388-2394 (2012).
  • Dodbiba, E., Xu,C.D., Payagala,T., Wanigasekara,E., Moon,M.H. and Armstrong,D.W. Use of ion pairing reagents for sensitive detection and separation of phospholipids in the positive ion mode LC-ESI-MS. Analyst, 136, 1586-1593 (2011).
  • Doehlert, D.C., Moreau,R.A., Welti,R., Roth,M.R. and McMullen,M.S. Polar lipids from oat kernels. Cereal Chem., 87, 467-474 (2010).
  • Donato, P., Cacciola,F., Cichello,F., Russo,M., Dugo,P. and Mondello,L. Determination of phospholipids in milk samples by means of hydrophilic interaction liquid chromatography coupled to evaporative light scattering and mass spectrometry detection. J. Chromatogr. A, 1218, 6476-6482 (2011).
  • Doria, M.L., Cotrim, Z., Macedo, B., Simoes, C., Domingues, P., Helguero, L. and Domingues, M.R. Lipidomic approach to identify patterns in phospholipid profiles and define class differences in mammary epithelial and breast cancer cells. Breast Cancer Res. Treatment, 133, 635-648 (2012).
  • Dubois, M., Tarres,A., Goldmann,T., Loeffelmann,G., Donaubauer,A. and Seefelder,W. Determination of seven glycidyl esters in edible oils by gel permeation chromatography extraction and liquid chromatography coupled to mass spectrometry detection. J. Agric. Food Chem., 59, 12291-12301 (2011).
  • Dugo, P., Fawzy, N., Cichello, F., Cacciola, F., Donato, P. and Mondello, L. Stop-flow comprehensive two-dimensional liquid chromatography combined with mass spectrometric detection for phospholipid analysis. J. Chromatogr. A, 1278, 46-53 (2013).
  • Dumlao, D.S., Buczynski,M.W., Norris,P.C., Harkewicz,R. and Dennis,E.A. High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. Biochim. Biophys. Acta, 1811, 724-736 (2011)
  • Eberlin, L.S., Ferreira,C.R., Dill,A.L., Ifa,DR. and Cooks,R.G. Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging. Biochim. Biophys. Acta, 1811, 946-960 (2011)
  • Eberlin, L.S., Ifa,D.R., Wu,C. and Cooks,R.G. Three-dimensional vizualization of mouse brain by lipid analysis using ambient ionization mass spectrometry. Angew. Chem.-Int. Ed., 49, 873-876 (2010).
  • Eberlin, L.S., Norton, I., Dill, A.L., Golby, A.J., Ligon, K.L., Santagata, S., Cooks, R.G. and Agar, N.Y.R. Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer Res., 72, 645-654 (2012).
  • Ecker, J. Profiling eicosanoids and phospholipids using LC-MS/MS: Principles and recent applications. J. Sep. Sci., 35, 1227-1235 (2012).
  • Ellis, S.R., Wu,C.P., Deeley,J.M., Zhu,X.J., Truscott,R.J.W., Panhuis,M.I.H., Cooks,R.G., Mitchell,T.W. and Blanksby,S.J. Imaging of human lens lipids by desorption electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom., 21, 2095-2104 (2010).
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Updated February 5, 2014