The science of lipidomics has been defined as "the full characterization of lipid molecular species and of their biological roles with respect to expression of proteins involved in lipid metabolism and function, including gene regulation". In other words, not only are comprehensive analyses required, but they must be related to the biological function of lipids through a knowledge of all enzymes, genes and other factors that may relevant, including the physical relationships of lipids in their membrane environments. Often, the data obtained are intended to shed light on human disease states. The primary impetus for the recognition of lipidomics as a discipline has been the emergence of new analytical technologies, especially those based on mass spectrometry, and these will be the main focus of this section of the Lipid Library.
- Shotgun lipidomics (Xianlin Han)
- Lipidomic analysis of glycerolipids (Robert C. Murphy)
- Parallel Mass Spectrometry (APCI-MS and ESI-MS) for Lipid Analysis (W. Craig Byrdwell)
- Characterization of lipids by MALDI mass spectrometry (Jackson O. Lay, Jennifer Gidden and Rohana Liyanage)
- Triacylglycerol Regioisomers Analysis (Dr. Tomáš Rezanka)
- Comprehensive Two Dimensional Gas Chromotography (GC x GC) for Lipid Analysis (Prof. Giorgia Purcaro)
Other contributions are under active discussion.
Relevant articles elsewhere on this website -
- Plant lipidomics (Ruth Welti) in the Plant Biochemistry section
- Lipidomics - a Personal View (William W. Christie) in the Selected Topics in Analysis section
Updated: September 8, 2015